Relationship Between Gastric Helicobacter pylori Infection and Colorectal Polyps: A Retrospective Cohort Study

Document Type : Research/Original Article

Authors

1 Departman of General Surgery, Erciş State Hospital, Van, Turkey

2 Departman of General Surgery, Izmir Katip Celebi University, Atatürk Education And Research Hospital, Izmir, Turkey

10.30476/acrr.2025.105645.1238

Abstract

Introduction: Gastric Helicobacter pylori (HP) infection is one of the most common bacterial infections worldwide. Recent reports have indicated that HP infection may also be a potential risk factor for colon polyps and cancer. In our study, we aimed to investigate whether there is an association between HP infection and colorectal polyps.
Methods: In the general surgery endoscopy unit of our hospital, patients who underwent gastroscopy and colonoscopy were analyzed in a cross-sectional and retrospective manner. Patients who could not tolerate the endoscopic procedure, those for whom HP assessment was not performed, those who had undergone HP eradication before the procedure, and those with gastrointestinal malignancies were excluded from the study. A logistic regression model was used to analyze the relationship between the prevalence of HP and colorectal polyps.
Results: A total of 310 patients were included in the current study. The rate of HP infection was found to be higher in patients with colorectal polyps compared to those without polyps (p<0.001). Age and the presence of multiple polyps were statistically higher in the HP-positive group (p=0.002 and p=0.023, respectively). When polyps were evaluated by size, location, type, and pathological subgroup, the rates of HP infection did not differ significantly between the groups.
Conclusions: Our study demonstrated that current gastric HP infection is associated with an increased risk of colorectal polyps. Patients with HP positivity may benefit from screening colonoscopy to prevent colorectal polyps and cancers.

Keywords


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