Serum and Salivary Calcium and Magnesium Levels in Inflammatory Bowel Disease: A Cross-Sectional Study

Document Type : Research/Original Article

Authors

1 Department of Physiology, School of Medicine, Aja University of Medical Sciences, Tehran, Iran

2 Department of Medical Mycology, School of Medicine, Aja University of Medical Sciences, Tehran, Iran

3 School of Medicine, Aja University of Medical Sciences, Tehran, Iran

10.30476/acrr.2024.103786.1225

Abstract

Background: Inflammatory bowel disease (IBD) is a chronic inflammation of the gastrointestinal tract with a relatively high occurrence and its cause has not yet been precisely identified. Since calcium and magnesium play a role in inflammatory processes, this study investigates the changes in the saliva and serum of people with inflammatory bowel disease (IBD).
Methods: This cross-sectional study included 30 subjects with IBD and 30 healthy individuals. Unstimulated saliva and serum were taken during a fasting state, and the amount of calcium and magnesium was measured by the photometric method. The data was analyzed using an unpaired Student’s t-test using SPSS version 22. P<0.05 is considered significant.
Results: The results showed that the amount of calcium and magnesium in the serum and saliva of patients with IBD was significantly lower than that of healthy individuals.
Conclusion: Calcium and magnesium levels appear to be significantly impaired and reduced in patients with inflammatory bowel disease (IBD). This deficiency can contribute to various complications associated with IBD and highlights the importance of monitoring and controlling mineral levels in these patients.

Keywords

Iranian Journal of Colorectal Research
Volume 12, Issue 3
September 2024
Pages 78-82

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