1. Lassen A, Hallas J, De Muckadell
O.B.S. Complicated a nd
uncomplicated peptic ulcers in
a Danish county 1993-2002: a
population-based cohort study. Am
J Gastroenterol 2006; 101: 945–953.
2. Xia B, Xia H.H.X, Ma C.W, et al.
Trends in the prevalence of peptic
ulcer disease and Helicobacter pylori
infection in family physician-referred
uninvestigated dyspeptic patients in
Hong Kong. Aliment Pharmacol Ther
2005; 22: 243–249.
3. Schiffmann L, Kahrau S, Berger G, et
al. Colon perforation in an adolescent
after short-term diclofenac intake.
ANZ J Surg 2005; 75: 726–727.
4. McCarthy D.M. Prevention and
treatment of gastrointestinal
symptoms and complications due
to NSAIDs. Best Pract Res Clin
Gastroenterol 2001; 15: 755–773.
5. Lambert M, Leven B, technology
RG-E science and, et al. New methods
of cleaning up heavy metal in soils
and water. Citeseer, http://citeseerx.
ist.psu.edu/viewdoc/download?doi=
10.1.1.400.2031&rep=rep1&type=pdf
(accessed 14 October 2021).
6. Jaishankar M, Tseten T, Anbalagan
N, et al. Toxicity, mechanism and
health effects of some heavy metals.
Interdiscip Toxicol 2014; 7: 60.
7. Losacco C, Perillo A. Metal-induced
oxidative Stress and Cellular
Signaling Alteration in Animals. Iran
J Appl Anim Sci 2018; 8: 367–373.
8. Odukanmi O. A, Salami A.T, Koda K,
et al. Trivalent Chromium Promotes
Healing of Experimental Colitis in
Mice by Suppression of Inflammation
and Oxidative Stress. J Biosci Med
2017; 5: 108–126.
9. Mertz W. Interaction of chromium
with insulin: A progress report. Nutr
Rev 1998; 56: 174–177.
10. Lv H, Lin Y, Liu P, et al. Protective effects
and potential underlying mechanisms
of sodium copper chlorophyllin against
ethanol-induced gastric ulcer in mice.
Acta Biochim Biophys Sin (Shanghai)
2019; 51: 925–933.
11. Yazdanpanah K, Parhizkar B,
Sheikhesmaeili F, et al. Efficacy of
zinc sulfate in peptic ulcer disease: A
randomized double-blind clinical trial
study. J Clin Diagnostic Res 2016; 10:
OC11–OC15.
12. Chromium - Health Professional
Fact Sheet, https://ods.od.nih.
g o v / f a c t s h e e t s / C h r o m i u m -
HealthProfessional/ (accessed 17
October 2021).
13. Sazakli E, Villanueva C.M.,
Kogevinas M, Maltezis K, Mouzaki
A. Chromium in Drinking Water:
Association with Biomarkers of
Exposure and Effect. Int J Environ
Res Publ Heal 2014; 11: 10125–10145.
14. Vincent J.B, Lukaski H. C. Chromium.
Adv Nutr 2018; 9: 505–506.
15. Scientific Opinion on Dietary
Reference Values for chromium.
EFSA J; 12. Epub ahead of print
1 October 2014. DOI: 10.2903/J.
EFSA.2014.3845.
16. Federal Register : Food Labeling:
Revision of the Nutrition and
Supplement Facts Labels, https://
w w w . f e d e r a l r e g i s t e r . g o v /
documents/2016/05/27/2016-11867/
food-labeli ng-revision- of-the-
nutrition-and-supplement-facts-labels
(accessed 17 October 2021).
17. Vincent J.B. The potential value and
toxicity of chromium picolinate as a
nutritional supplement, weight loss
agent and muscle development agent.
Sports Med 2003; 33: 213–230.
18. Nakada M, Demura S. The effect of
past and present lifestyle, nutrition
habits, and gender on bone mineral
density. Health (Irvine Calif) 2010;
02: 713–721.
19. Odukanmi O.A, Owoeye O, Salami
A. T, Morakinyo O.L., Iyiola O.T
and Olaleye S.B. Effect of trivalent
chromium (Cr2O3 ) on stomach
morphometry and some vital organs
in male wistar rats | African Journal
of Medicine and Medical Sciences.
Afr J Med Med Sci 2019; 48: 329–337.
20. Kareema H, Dohan A-H, Abbas H.
Effects of Potassium Dichromate on
Reproduction and Fertility in Albino
Female Mice. Int J PharmTech Res
2016; 2016: 205–213.
21. Amagase K, Okabe S. Acetic acid
ulcers: a new method for producing
solitary chronic ulcers in rat stomachs
by intraluminal application of acetic
acid solution. InflammoPharmacology
2002 104 2002; 10: 385–389.
22. Gornall AG, Bardawill CJ, David
MM. Determination of serum proteins
using the biuret reaction. Epub
ahead of print 1949. DOI: 10.1016/
S0021-9258(18)57021-6.
23. Varshney R, Kale R.K. Effects of
calmodulin antagonists on radiation-
induced lipid peroxidation in
microsomes. Int J Radiat Biol 1990;
58: 733–743.
24. Sinha A.K. Colorimetric assay of
catalase. Anal Biochem 1972; 47:
389–394.
25. Beauchamp C, Fridovich I. Superoxide
dismutase: Improved assays and an
assay applicable to acrylamide gels.
Anal Biochem 1971; 44: 276–287.
26. Ignarro, L.J., Buga, G.M., Wood, K.S.,
Byrns, R.E., and Chaudhuri, G. 1987.
Endothelium-Derived relaxing factor
produced and released from artery
and vein is nitric oxide. Proc. Natl.
Acad. Sci. U.S.A. 84(24): 9265–9269
27. Kim H, Wei Y, Lee JY, et al.
Myeloperoxidase Inhibition Increases
Neurogenesis after Ischemic Stroke. J
Pharmacol Exp Ther 2016; 359: 262.
28. Vandesompele J, De Preter K, Pattyn
F, et al. Accurate normalization of
real-time quantitative RT-PCR data
by geometric averaging of multiple
internal control genes. Genome Biol
2002; 3: 1–12.
29. Animals NRC (US.) C for the U of
the G for the C and U of L. Guide
for the Care and Use of Laboratory
Animals. Guid Care Use Lab Anim.
Epub ahead of print 27 December
2011. DOI: 10.17226/12910.
30. Qing C. The molecular biology
in wound healing & non-healing
wound. Chinese J Traumatol 2017;
20: 189–193. 31. Phillipson M, Kubes P. The neutrophil
in vascular inflammation. Nat Med
2011; 17: 1381–1390.
32. Peiseler M, Kubes P. More friend than
foe: The emerging role of neutrophils
in tissue repair. J Clin Invest 2019;
129: 2629–2639.
33. Hottz ED, Paula Monteiro AT,
Bozza FA, et al. Review Article
Inflammasome in Platelets: Allying
Coagulation and Inflammation in
Infectious and Sterile Diseases?
Epub ahead of print 2015. DOI:
10.1155/2015/435783.
34. Andia I, Sanchez M, Maffulli N.
Tendon healing and platelet-rich
plasma therapies. Expert Opin Biol
Ther 2010; 10: 1415–1426.
35. Halpern BC, Chaudhury S, Rodeo
SA. The Role of Platelet-Rich Plasma
in Inducing Musculoskeletal Tissue
Healing: https://doi.org/101007/
s11420-011-9239-7 2012; 8: 137–145.
36. Davis VL, Abukabda AB, Radio
NM, et al. Platelet-rich preparations
to improve healing. Part II: platelet
activation and enrichment, leukocyte
inclusion, and other selection criteria.
J Oral Implantol 2014; 40: 511–521.
37. Demidova-Rice TN, Hamblin MR,
Herman IM. Acute and impaired
wound healing: pathophysiology and
current methods for drug delivery,
part 1: normal and chronic wounds:
biology, causes, and approaches to
care. Adv Skin Wound Care 2012; 25:
304–314.
38. Zimmerman G.A, Weyrich A.S.
Signal-Dependent Protein Synthesis
by Activated Platelets New Pathways
to Altered Phenotype and Function.
Arterioscler Thromb Vasc Biol 2008;
28: s17.
39. Parrish W.R. Physiology of Blood
Components in Wound Healing:
an Appreciation of Cellular
Co-Operativity in Platelet Rich
Plasma Action. J Exerc Sport Orthop
2017; 4: 1–14.
40. Conti V, Izzo V, Corbi G, et al.
Antioxidant Supplementation in
the Treatment of Aging-Associated
Diseases. Front Pharmacol; 7. Epub
ahead of print 12 February 2016. DOI:
10.3389/FPHAR.2016.00024.
41. Hwang J, Jin J, Jeon S, et al. SOD1
suppresses pro-inflammatory immune
responses by protecting against
oxidative stress in colitis. Redox Biol
2020; 37: 101760.
42. Balali-Mood M, Naseri K, Tahergorabi
Z, et al. Toxic Mechanisms of Five
Heavy Metals: Mercury, Lead,
Chromium, Cadmium, and Arsenic.
Front Pharmacol 2021; 12: 227.
43. Kangralkar, V.A, Patil, S.D,
Bandivadekar R. Oxidative stress and
diabetes: a review. Int J Pharm Appl
2010; 1: 38-45.
44. Porfire A.S, Leucuţa SE, Kiss B,
et al. Investigation into the role of
Cu/Zn-SOD delivery system on its
antioxidant and anti-inflammatory
activity in rat model of peritonitis.
Pharmacol Rep 2014; 66: 670–676.
45. Satish L, Kathju S. Cellular and
Molecular Characteristics of
Scarless versus Fibrotic Wound
Healing. Dermatol Res Pract; 2010.
Epub ahead of print 2010. DOI:
10.1155/2010/790234.
46. Schultz G.S, Chin G.A, Moldawer L,
et al. Principles of Wound Healing.
Diabet Foot Probl 2011; 395–402.
47. Sziksz E, Pap D, Lippai R, et al.
Fibrosis Related Inf lammatory
Mediators: Role of the IL-10 Cytokine
Family. Mediators Inflamm; 2015.
Epub ahead of print 2015. DOI:
10.1155/2015/764641
)