Celiac disease and other autoimmune manifestation in a 9 years old girl

Document Type : Case Report

Authors

1 Pediatric Gastroenterology and Hepatology Research Center, Tehran University of Medical Sciences, Tehran, Iran

2 Tehran university of medical sciences,Tehran,Iran

3 Department of internal medicine , Zabol university of medical sciences, Zabol, Iran

Abstract

Celiac disease (CD) is an autoimmune disease with high incidence of multi organ involvement; particularly, Gastrointestinal manifestations and a redoubled risk of malignancies. Here we tend to report a case of CD , reaction anemia (AIHA). who presented to us with history of abdominal pain fever and nausea and vomiting .her examination finding was anemia and spelenomegaly her laboratory tests showed increase liver enzymes and macrocytosis anemia with positive coombs without decrease in hemoglobin and high retic cell .Poly autoimmunity needs comprehensive analysis. , AIHA and CD were diagnosed throughout the admission upon in depth work-up. Similarly, alternative reaction etiologies,All diseases were treated with strict adherence to a diet (GFD) and cortico steroid therapy. This was a rare case a case of celiac presenting with such a good array of signs and symptoms has seldom been reportable within the literature and also the management of this patient was distinctive and difficult

Keywords


  1.  Kelly, C.P., et al., Advances in diagnosis and management of celiac disease. Gastroenterology, 2015. 148(6): p. 1175-86.
  2. Bianco, C., et al., Diagnosis and Management of Autoimmune Hemolytic Anemia in Patients with Liver and Bowel Disorders. J Clin Med, 2021. 10(3).
  3. Liebman, H.A. and I.C. Weitz, Autoimmune Hemolytic Anemia. Med Clin North Am, 2017. 101(2): p. 351-359.
  4. Michel, M., et al., The spectrum of Evans syndrome in adults: new insight into the disease based on the analysis of 68 cases. Blood, 2009. 114(15): p. 3167-72.
  5. Fasano, A., Systemic autoimmune disorders in celiac disease. Curr Opin Gastroenterol, 2006. 22(6): p. 674-9.