Preoperative Bowel Preparation with Oral Antibiotics Might Increase Wound Infection in Elective Colorectal Resections

Aghaei-Afshar, Mahmoud; Mahmoudikordi, Farzaneh; Rezazadehkermani, Mohammad

Preoperative Bowel Preparation with Oral Antibiotics Might Increase Wound Infection in Elective Colorectal Resections

Document Type : Brief Report

Authors

Mahmoud Aghaei-Afshar ¹

Farzaneh Mahmoudikordi ²

Mohammad Rezazadehkermani ¹

¹ Department of General Surgery, Kerman University of Medical Sciences, Kerman, Iran

² Department of Food Hygiene and Quality Control, Shahrekord University, Shahrekord, Iran

Abstract

Preoperative bowel preparation was previously strictly done for all patient undergoing colorectal surgeries. With advances in the
surgical techniquesandpatient care, the role of bowel preparation in surgical complications is questioned. In this studywedescribe
a non-randomized retrospective analysis of 193 patients who underwent left colon and rectal resections in two different hospitals,
the preoperative bowel preparation regimens were different in two hospitals. Both regimens contain mechanical preparation with
polyethylene glycol, however, one hospital administered erythromycin and neomycin and the other hospital did not. From 74 patients
receiving oral antibiotic eight (10.8%) one developedwoundinfection and from 119 patientswhodid not receive oral antibiotic
three (2.5%) patient developed wound infection. This difference was statistically significant. Regarding literature review, it is suggested
to omit oral antibiotic from preoperative bowel preparation regimens elective colorectal resections.

Keywords

Neomycin

Erythromycin

Colectomy

Infection