1
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
2
Gasteroenterohepatology Research Center, Nemazee Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran
3
Department of Biochemistry, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran
Abstract
Context: The incidence of colorectal cancer has significantly increased in Iran during the last decade. Accumulating evidence suggests that there is a significant correlation between genetic variations such as polymorphisms and colorectal cancer. Therefore, identification of critical polymorphisms related to colorectal cancer can contribute to find individuals at high risk of CRC. Evidence Acquisition: The focus of this review was on published articles in English about the association between different single nucleotide polymorphisms and colorectal cancer in the Iranian population. Evidences were gathered by searching online medical databases including Google scholar, Pubmed, Scopus and Science Direct. Conclusions: Various single nucleotide polymorphisms of critical genes indicated significant association with colorectal cancer in the Iranian population. New polymorphism markers for high risk individuals have been recognized through further investigations to reduce the incidence and mortality of colorectal cancer.
Zamani, M., Hosseini, S. V. & Mokarram, P. (2016). The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population. (e47146). Iranian Journal of Colorectal Research, 4(3), e47146
MLA
Zamani, M., Hosseini, S. V., & Mokarram, P. "The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population" .e47146 , Iranian Journal of Colorectal Research, 4, 3, 2016, e47146.
HARVARD
Zamani, M., Hosseini, S. V., & Mokarram, P. (2016). 'The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population', Iranian Journal of Colorectal Research, 4(3), e47146.
CHICAGO
Zamani, M., Hosseini, S. V. & Mokarram, P., "The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population." Iranian Journal of Colorectal Research, 4 3 (2016): e47146,
VANCOUVER
Zamani M., Hosseini S. V., Mokarram P. The Correlation Between Single Nucleotide Polymorphism Patterns and Colorectal Cancer in the Iranian Population. Iran. J. Colorectal. Res. 2016;4(3):e47146.