Iranian Journal of Colorectal Research

Iranian Journal of Colorectal Research

The Effect of Oral Psyllium Herbal Laxative Powder in Prevention of Hemorrhoids and Anal Fissure during Pregnancy, a Randomized Double Blind Clinical Trial

Authors
Buddhike Sri Harsha Indrasena 1
Leila Ghahramani 2
Seyed Vahid Hosseini 2
Salar Rahimikazerooni 2
Ali Mohammad Bananzadeh 2
Bahia Namavar Jahromi 3
Alamtaj Samsam 3
Abbas Rezaeian Zadeh 4
Ali Reza Safarpour
Ali Bagherpour Jahromi 2
Seyed Hesamaddin Banihashemi 5
1 Department of Surgery, Teaching Hospital Batticaloa, Batticaloa, Sri Lanka
2 Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, IR Iran
4 Department of Epidemiology, Shiraz University of Medical Sciences, Shiraz, IR Iran
5 Department of Surgery, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
10.17795/acr-11488
Abstract
Background Pregnancy and delivery make susceptible women to hemorrhoidal disease and fissure during pregnancy because of an increase in abdominal pressure and constipation. Objectives We aimed to determine the preventative effect of psyllium powder (herbal laxative) on constipation, anal fissure and hemorrhoidal diseases during pregnancy. Patients and Methods Regarding the properties of oral psyllium powder, in this study, we aimed to determine the preventative effect of psyllium powder on constipation, anal fissure and hemorrhoidal diseases during pregnancy. This is a randomized clinical trial. All primigravid women, aging 20-30, at the onset of 3rd trimester who referred to OB clinic of Shiraz university of medical sciences were divided into two groups. Treatment group received psyllium powder twice daily while control group received placebo. All cases were evaluated two times before delivery and occurrence of constipation and fissure and hemorrhoid were assessed by a single team. Results The mean and SD of age in group A (psyllium consumption group) was 29.9 ± 2.24 and in group B (placebo group) was 29.5 ± 2.48. Comparison between three outcome variables (hemorrhoid, fissure and constipation) revealed significant difference in group A and group B in compare with group B, p < 0.001). Conclusions According to our study psyllium powder consumption during the third trimester of pregnancy could significantly prevent constipation, hemorrhoid anal fissure.
Keywords
Laxatives
Psyllium
Constipation
Hemorrhoid
Fissure
Haemorrhoids
Pregnancy
Psyllium powder
Iranian Journal of Colorectal Research
Volume 1, Issue 3
Autumn 2013
Pages 2-7