Sporadic Congenital Hyperplasia of Interstitial Cell of Cajal of Rectum as a Cause of Chronic Constipation

Bananzadeh, Alimohammad; Geramizadeh, Bita; Moslemi, Sam; Ghahramani, Leila; Safarpour, Alireza; Hosseini, Seyed Vahid; Izadpanah, Ahmad

doi:10.17795/acr-11479

Sporadic Congenital Hyperplasia of Interstitial Cell of Cajal of Rectum as a Cause of Chronic Constipation

Authors

Alimohammad Bananzadeh ¹

Bita Geramizadeh ²

Sam Moslemi ³

Leila Ghahramani

Alireza Safarpour ¹

Seyed Vahid Hosseini ¹

Ahmad Izadpanah ¹

¹ Colorectal research center, Shiraz University of Medical Sciences, Shiraz, IR Iran

² Department of Pathology, Shiraz University of Medical Sciences, Shiraz, IR Iran

³ Department of Surgery, Shiraz University of Medical Sciences, Shiraz, IR Iran

10.17795/acr-11479

Abstract

Gastrointestinal stromal tumors (GIST) are the usual primary mesenchymal neoplasms of the GI tract. Interstitial cells of Cajal (ICCs) are intestinal pacemaker cells that instigate peristalsis in the stomach and intestine, and are measured to be precursors of GIST. We are reporting a 17 year old boy with chronic constipation since childhood and a huge rectum in abdominal radiography, who underwent exploratory laparotomy, resection of huge rectum and construction of sigmoid colostomy. Pathology report was "Hyperplasia of Interstitial Cells of Cajal".

Keywords

Gastrointestinal stromal tumor (GIST)

ICC hyperplasia

Chronic Constipation