TY - JOUR ID - 45966 TI - Desmoid tumor initially unresectable – About two cases JO - Iranian Journal of Colorectal Research JA - ACRR LA - en SN - AU - Senti Farraraons, Sara AU - Estival Gonzalez, Anna AU - Velazquez, Cuadrado AU - Gene Skrabec, Clara AU - Camps Ausas, Ignasi AD - Department of General Surgery, Hospital Universitari Germans Trias i Pujol, Barcelona AD - Department of Oncology, Hospital Germans Trias i Pujol, Barcelona Y1 - 2019 PY - 2019 VL - 7 IS - 4 SP - 1 EP - 4 KW - desmoid KW - Surgery KW - Oncology KW - Tumour DO - 10.30476/acrr.2019.45966 N2 - Desmoid tumor, also called aggressive fibromatosis, is a rare fibroblastic proliferation of connective tissue and skeletal muscle aponeurosis. The aetiology of desmoid tumours is poorly understood, but they have been related with oestrogen stimuli, previous trauma, surgical interventions and pregnancy. Although it is characterized by not having potential for metastasize or differentiate, it is a non-encapsulated lesion, with an infiltrative growth and unpredictable behaviour. In this way, it could have either an aggressive pattern, when compared with other low degree malignancy sarcomas, or a very indolent one, even with spontaneous regression. Therapeutic options in desmoid tumours have been changing over these last years, as surgery upfront in asymptomatic patients has been superseded by active surveillance. However, treatment has to be individualized in some specific scenarios such as intra-abdominal lesions. We present two cases of patients diagnosed with an intra-abdominal desmoid tumour with threatening behaviour, the treatment approach and final resolution. UR - https://colorectalresearch.sums.ac.ir/article_45966.html L1 - https://colorectalresearch.sums.ac.ir/article_45966_d0e1902a040e5d559a146f0ea0f0f93f.pdf ER -