ORIGINAL_ARTICLE
Systematic Review of Fecal and Mucosa-Associated Microbiota Compositional Shifts in Colorectal Cancer
Introduction: Gut microbiota is a major component of the intestinal luminal environment and plays important roles in colorectal cancer. Object: systematically review all the existing literature on the association of mucosa-associated and fecal microbiota with incidence, location, and stage of colorectal adenoma and carcinoma. Methods: The scientific search was done up to July 2018. The search was limited to the English language with predefined and proper keywords. Among 616 articles some of them were eliminated due to some reasons. The inclusion and exclusion criteria were defined. In the next step two reviewers (M.M and Z.K) independently scanned the titles of all retrieved articles, removed duplicates, and identified potentially relevant abstracts for further assessment. The Newcastle-Ottawa Scale (NOS) for assessing the Quality was used for quality control. Result: Finally, 54 articles were entered into the study. Fusobacteria 39 (72%), Firmicutes 22(40%), Bacteroidetes 20 (37%), Proteobacteria 15(27%), Actinobacteria 10(18%) was the most prevalent phylum which was found in colorectal cancer patients. Among these taxa some of them were increased in colorectal cancer patients compared to the control; on the other hand, some taxon was declined in colorectal cancer patients. Besides this, in some taxon there were controversies among articles. Conclusion: Early detection of CRC is essential because patients whose cancer are detected at an early stage have more chance of survival. Until now there are several studies have demonstrated the potential rule of gut microbiota to be used for detection of CRC, but there is not any predefining protocol for screening. Although we found lots of articles which were published in this area, for defining a precise microbiota profile we need large multicenter case-control studies, where can show the effect of most important confounding factors like nutrition, ethnicity, physical activity, smoking consumption, and genetic background.
https://colorectalresearch.sums.ac.ir/article_46747_0238a471593e4723c177d764770c67a2.pdf
2020-06-01
41
64
10.30476/acrr.2020.46747
Colorectal cancer
Colorectal neoplasm
CRC
Screening
Microbiota
Zahra
Karimi
zahrakarimi1532@gmail.com
1
Nursing Student, Nursing & Midwifery Faculty, Bushehr Universiity of Medical Sciences, Bushehr, Iran
AUTHOR
Arash
Ghazbani
arashghazbani1378@gmail.com
2
Student Research Committee, Bushehr University of Medical Sciences, Bushehr, Iran
AUTHOR
Sara
Kashefian Naeeini
kashefian@gmail.com
3
Department of English Language, Faculty of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
AUTHOR
Maryam
Marzban
marzbanh@gmail.com
4
Department of Epidemiology and Biostatistics, School of Public Health Bushehr University of Medical Sciences; Bushehr, Iran.
LEAD_AUTHOR
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56
ORIGINAL_ARTICLE
Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review
Lateral pelvic lymph node dissection for advanced low rectal cancer has generated much discussion in the literature in last few years. Whilst it is still being debated as to whether it constitutes a locoregional disease amenable to surgery, or whether it is a distant metastases requiring neoadjuvant therapy, what is clear is that patients with enlarged lateral pelvic lymph nodes have higher rate of recurrence. In this review, we have analysed the current evidence and recommendations for lateral pelvic lymph node dissection. If advanced low rectal cancer (stage II, stage III) below peritoneal reflection, the decision to perform LPLND depends on (1) size of LPLN on MRI (>5mm) prior to neoadjuvant chemoradiotherapy and (2) non-responsive LPLN after CRT (LPLN >5mm before and after CRT). LPLN does prolong the operating time, and greater blood loss, however, is not associated with any greater morbidity. Preservation of the neurovascular structures, including the obturator nerves, hypogastric nerves, and the inferior vesical arteries must be identified and preserved. We have also described the key steps in performing lateral pelvic lymph node dissection.
https://colorectalresearch.sums.ac.ir/article_46703_a9310a12b18a661b9c07e9f190b0751e.pdf
2020-06-01
65
74
10.30476/acrr.2020.46703
lateral pelvic lymph node
low rectal cancer
neoadjuvant therapy
JU YONG
CHEONG
santiago-james@hotmail.com
1
Royal Prince Alfred Hospital, Sydney, Australia
LEAD_AUTHOR
Peter
Lee
pjmlee23@gmail.com
2
Department of Colorectal Surgery, Royal Prince Alfred Hospital
AUTHOR
Yoon Suk
Lee
leekcmc@gmail.com
3
Seoul St Mary’s Hospital, Catholic Medical Center, Seoul, South Korea
AUTHOR
Nariman
Ahmadi
nariman179@hotmail.com
4
Chris O’Brien Lifehouse, Sydney, Australia
AUTHOR
Takahashi T, Ueno M, Azekura K, Ohta H. Lateral node dissection and total mesorectal excision for rectal cancer. Disease of colon and rectum 2000; 43: 59-68.
1
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Ueno H, Mochizuki H, Hashiguchi Y, Hase K. Prognostic determinants of patients with lateral noal involvement by rectal cancer. Annals of Surgery 2001; 234: 190-197.
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4
Ueno H, Mochizuki H, Hashiguchi Y, Ishiguro M, Miyoshi M. Potential prognostic benefit of lateral pelvic node dissection for rectal cancer located below the peritoneal reflection. Annals of Surgery 2007;245: 80-87.
5
Shihab O, Taylor F, Bees N, Blake H. Relevance of magnetic resonance imaging-detected pelvic sidewall lymph node involvement in rectal cancer. British Journal of Surgery 2011; 98: 1798-1804.
6
Heald R, Husband E, Ryall R. The mesorectum in rectal cancer surgery-the clue to pelvic recurrence? British Journal of Surgery 1982;69: 613-616.
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Akiyoshi T, Watanabe T, Miyata S, Kotake K, Muto T, Sugihara K. Results of a Japanese nationwide multi-institutional study on LPLN metastasis in low rectal cancer: is it regional or distant metastases? Annals of Surgery 2012; 255: 1129-1134.
8
Georgiou P, Tan E, Gouvas N, Antoniou A, Brown G, Nicholls R, Tekkis P. Extended lymphadenectomy versus conventional surgery for rectal cancer: a meta-analysis. Lancet Oncology 2009; 10: 1053-1062.
9
Kuster M, Beets G, Van de Valde C. A comparison betwen the treatment of low rectal cancer in Japan and the Netherlands, focusing on the patterns of local recurrence. Annals of Surgery 2009; 249: 229-235.
10
Ogura A, Konishi T, Cunningham C, Garcia-Aguilar J, Iversen H, Toda S, et al. Neoadjuvant (Chemo)radiotherapy With Total Mesorectal Excision Only Is Not Sufficient to Prevent Lateral Local Recurrence in Enlarged Nodes: Results of the Multicenter Lateral node study of patients with low cT3/4 rectal cancer. Journal of Clinical Oncology 2019; 37: 33-43.
11
Kim T, Park W, Choi D, Park H, Kim S, Cho Y, et al. Factors associated with lateral pelvic recurrence after curative resection following neoadjuvant chemoradiotherapy in rectal cancer patients. International journal of colorectal disease 2014; 29: 193-200.
12
Kim M, Kim T, Kim D, Kim S, Baek J, Chang H, et al. Can chemoradiation allow for omission of lateral pelvic node dissection for locally advanced rectal cancer? Journal of Surgical Oncology 2015; 111: 459-464.
13
Kim T, Jeong S, Choi D, Kim D, Jung K, Moon S, et al. Lateral lymph node metastasis is a major cause of locoregional recurrence in rectal cancer treated with preoperative chemoradiotherapy and curative resection. Annals of surgical oncology 2008; 15: 729-737.
14
Kusters M, Slater A, Muirhead R, Hompes R, Guy R, Jones O, et al. What to do with lateral nodal disease in low locally advanced rectal cancer? a call for further reflection and research. Disease of colon and rectum 2017; 60: 577-585.
15
Ogawa S, Hida J, Ike H, Kinugasa T, Ota M, Shinto E, et al. Selection of lymph node-positive cases based on perirectal and LPLNs using magnetic resonance imaging: study of the Japanese society for cancer of the colon and rectum. Annals of surgical oncology 2016; 23: 1187-1194.
16
Ogawa S, Hida J, Ike H, Shinto E, Itabashi M, Okamoto T, et al. The important risk factor for LPLN metastasis of lower rectal cancer is node-positive status on magnetic resonance imaging: study of the Lymph Node Committee of Japanese Society for Cancer of the Colon and Rectum. International Journal of colorectal disease 2016; 31: 1719-1728.
17
Lee D, Matsuda T, Yamashita K, Hasegawa H, Yamamoto M, Kanaji S, et al. Significance of LPLN Size in Predicting Metastasis and Prognosis in Rectal Cancer. Anticancer research 2019; 39: 993-998.
18
Akiyoshi T, Matsueda K, Hiratsuka M, Unno T, Nagasaki T, Konishi T, et al. Indications for LPLN Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer. Annals of surgical oncology 2015; suppl 3: 614-620.
19
Kim M, Park SC, Kim T, Kim D, Kim S, Baek J, et al. Is lateral pelvic node dissection necessary after preoperative chemoradiotherapy for rectalcancer patients with initially suspected lateral pelvic node? Surgery 2016; 160: 366-376.
20
Oh H, Kang S, Lee S, Lee S, Ihn M, Kim D, et al. Neoadjuvant chemoradiotherapy affects the indications for lateral pelvic node dissection in mid/low rectal cancer with clinically suspected lateral node involvement: a multicenter retrospective cohort study. Annals of surgical oncology 2014; 21: 2280-2287.
21
Fujita S, Mizusawa J, Kinugasa Y, Komori K, Ohue M, Ota M, et al. Mesorectal Excision With or Without Lateral Lymph Node Dissection for Clinical Stage II/III Lower Rectal Cancer (JCOG0212): A Multicenter, Randomized Controlled, Noninferiority Trial. Annals of Surgery 2017; 266: 201-207.
22
Komori K, Fujita S, Mizusawa J, Kanemitsu Y, Ito M. Predictive factors of pathological LPLN metastasis in patients without clinical LPLN metastasis (clinical stage II/III): The analysis of data from the clinical trial (JCOG0212). European journal of surgical oncology 2019; 45: 336-340.
23
Fujita S, Akasu T, Mizusawa J, Kinugasa Y. Postoperative morbidity and mortality after mesorectal excision with and without lateral lymph node dissection for clinical stage II or stage III lower rectal cancer (JCOG0212): results from a multicentre, randomized controlled, non-inferiority trial. Lancet oncology 2012; 13: 616-621.
24
Moriya Y, Hojo K, Sawada T, Koyama Y. Significance of lateral node dissection for advanced rectal carcinoma at or below the peritoneal reflections. Disease of colon and rectum 1989; 32: 307-315.
25
Kim M, Oh J. Lateral lymph node dissection with the focus on indications, functional outcomes, and minimally invasive surgery. Annals of Coloproctology 2018; 34: 229-223.
26
Saito S, Fujita S, Mizusawa J, Kanemitsu Y, Saito N, Kinugasa Y, et al. Male sexual dysfunction after rectal cancer surgery: Results of a randomized trial comparing mesorectal excision with and without lateral lymph node dissection for patients with lower rectal cancer: Japan Clinical Oncology Group Study JCOG0212. European Journal of surgical oncology 2016; 42: 1851-1858.
27
Manabe T, Koga Y, Kubo H, Baba K, Nagayoshi K, Nagai S. Adverse effects on the post-operative urinary function after combined resection of inferior vesical artery in laparoscopic LPLN dissection: retrospective analysis of consecutive 95 series. Surgical laparoscopy, endoscopy & percutaneous techniques 2019; Epub ahead of print. doi: 10.1097/SLE.0000000000000681
28
ORIGINAL_ARTICLE
Distal Margin Shrinkage Factor – A Consideration Before Dividing the Specimen in Colorectal Cancer Surgery
Background - The risk of local recurrence in colorectal cancer has been associated with the length of clear distal margin in the specimen taken during original resection. It has been reported that there is significant specimen shrinkage after fixation in formalin. This study is aimed to quantify this degree of shrinkage and to investigate the factors for specimen shrinkage. Methods – This research was a single centre prospective study. All adult patients who underwent colorectal surgery for cancer had demographics, surgical details and cancer staging and pathology recorded. Colonic specimens were measured immediately post resection including the total length, the mesenteric length and the distal length from the palpable tumour. Multiple logistic linear regression was applied to identify factors associated with distal margin shrinkage. Results – Right-sided colectomy specimens had an inconsistent degree of shrinkage. Left-sided colectomy specimens showed an average shrinkage of 20% (CI 4% – 36%). The only other factor observed that had statistically significant association on the shrinkage of distal margins in specimens was increasing tumour size. Conclusions - Specimens resected during anterior resection for colorectal cancer have a consistent level of shrinkage. Locally advanced tumours were observed to have an association with specimen distal margin shrinkage, however the mechanism is unclear. This new evidence can assist intra-operative decision making to allow adequate distal margin resection.
https://colorectalresearch.sums.ac.ir/article_46702_81428cf1d3091800242ae67b55e5ec5d.pdf
2020-06-01
75
78
10.30476/acrr.2020.46702
Colorectal neoplasm
Colorectal Surgery
formalin
margins of excision
Yiu
Ho
mingho113@gmail.com
1
Department of Digestive Diseases, Royal Sussex County Hospital, Eastern Road, Brighton, BN2 5BE, United Kingdom
AUTHOR
Jai
Hoff
jaihoff90@gmail.com
2
Surgical Department, Rockhampton Hospital, Rockhampton
LEAD_AUTHOR
Andrew
May
may.andrewd@gmail.com
3
Surgical Department, Rockhampton Hospital, Rockhampton
AUTHOR
Clay
Renwick
dr.clayrenwick@gmail.com
4
Surgical Department, Rockhampton Hospital, Rockhampton
AUTHOR
Monson JR, Weiser MR, Buie WD, Chang GJ, Rafferty JF, Buie WD, Rafferty J. Practice parameters for the management of rectal cancer (revised). Dis Colon Rectum 2013; 56:535.
1
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Sjövall A, Granath F, Cedermark B, Glimelius B, Holm T. Loco-regional recurrence from colon cancer: a population-based study. Ann Surg Oncol 2007; 14:432.
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Kim YW, Kim NK, Min BS, et al. Factors associated with anastomotic recurrence after total mesorectal excision in rectal cancer patients. J Surg Oncol 2009; 99:58.
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6
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Tran T, Sundaram CP, Bahler CD, Eble JN, Grignon DJ, Monn MF, Simper NB, Cheng L. Correcting the Shrinkage Effects of Formalin Fixation and Tissue Processing for Renal Tumors: toward Standardization Ho YM et al. 78 Ann Colorectal Res 2020;8(2) of Pathological Reporting of Tumor Size. J Cancer. 2015 Jul 2;6(8):759-66.
16
Kwok SP, Lau WY, Leung KL, Liew CT, Li AK. Prospective analysis of the distal margin of clearance in anterior resec- tion for rectal carcinoma. Br J Surg. 1996;83:969-972.
17
Battersby NJ, Juul T, Christensen P, et al. Predicting the Risk of BowelRelated Quality-of-Life Impairment After Restorative Resection for Rectal Cancer: A Multicenter CrossSectional Study. Dis Colon Rectum. 2016;59(4):270-280.
18
Patel SA, Chen YH, Hornick JL, Catalano P, Nowak JA, Zukerberg LR, Bleday R, Shellito PC, Hong TS, Mamon HJ. Early-stage rectal cancer: clinical and pathologic prognostic markers of time to local recurrence and overall survival after resection. Dis Colon Rectum. 2014 Apr;57(4):449-59.
19
Zeng WG, Liu MJ, Zhou ZX, Wang ZJ. A Distal Resection Margin of ≤1mm and Rectal Cancer Recurrence After Sphincter-Preserving Surgery: The Role of a Positive Distal Margin in Rectal Cancer Surgery. Dis Colon Rectum. 2017 Nov;60(11):1175-83.
20
ORIGINAL_ARTICLE
The effect of humidified warmed CO2 during open colorectal surgery on body temperature and postoperative pain: a randomized controlled trial.
Introduction: Open abdominal surgery exposes the intestine to negative ventilation (20°C, 0-5% RH), which along with the large surface area of peritoneum has the potential to cause loss of body heat. This study examined whether the warmed, humidified CO2 (WHCO2) can reduce heat loss and reduce postoperative pain. Methods: A randomized controlled trial was performed at a tertiary colorectal unit (Concord Repatriation General Hospital, The University of Sydney, Australia). The study group received WHCO2 at a rate of 10L/min. The control group did not receive any insufflation during the operation. Patients were over 18 years of age undergoing elective open colorectal operations. Core body temperature measurement was made every 15 minutely with a trans-oesophageal probe. Postoperative pain was assessed via: (1) duration of use of patient controlled analgesia (PCA), (2) total oral morphine equivalent daily dose (oral MEDD). Results: 39 Patients were recruited in the study, with 20 patients receiving WHCO2. There was no difference in the core body temperature between the WHCO2 and the Control group (36.1 vs. 35.9°C, p=0.35). There was no difference in the % of the operating time where core body temperature dropped below the lower limit of normal of 35.8°C (28.4% vs 35.8%, p=0.51), or to the level of hypothermia of 35°C (7.7% vs. 13.4%, p=0.50). No difference in postoperative PCA duration, as well as MEDD, were noted between the CO2 group and control group. Conclusion: WHCO2 had no effect on core body temperature during open colorectal surgery and the postoperative pain experienced.
https://colorectalresearch.sums.ac.ir/article_46746_3f539f3f40904289f3a8b091f00e1514.pdf
2020-06-01
79
87
10.30476/acrr.2020.46746
Humidified, warmed Carbon dioxide
Pneumoperitoneum
Core body temperature
Postoperative pain
Colorectal Surgery
JU YONG
CHEONG
santiago-james@hotmail.com
1
Department of Colorectal Surgical, Concord Repatriation General Hospital, Sydney, Australia- Discipline of Pathology, Charles Perkins Centre, Sydney Medical School, The University of Sydney, Sydney, Australia
LEAD_AUTHOR
Anil
Keshava
anilkeshava@gmail.com
2
Department of Colorectal Surgical, Concord Repatriation General Hospital, Sydney, Australia
AUTHOR
Christopher
Young
cyoungnsw@aol.com
3
Department of Colorectal Surgical, Concord Repatriation General Hospital, Sydney, Australia
AUTHOR
M. Persson and J. van Der Linden, “Intraoperative CO2 insufflation can decrease the risk of surgical site infection,” Medical Hypothesis, vol. 71, no. 1, pp. 8-13, 2008.
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S. Davis, D. Mikami, M. Newlin, B. Needleman, M. Barrett, R. Fries, T. Larson, J. Dundon, M. Goldblatt and W. Melvin, “Heating and humidifying of carbon dioxide during pneumoperitoneum is not indicated: a prospective randomized trial,” Surgical Endoscopy, vol. 20, no. 1, pp. 153-158, 2006.
18
B. Klugsberger, M. Schreiner, A. Rothe, D. Haas, P. Oppelt and A. Shamiyeh, “Warmed, humidified carbon dioxide insufflation versus standard carbon dioxide in laparoscopic cholecystectomy: a double-blinded randomized controlled trial.,” Surgical Endoscopy, vol. 28, no. 9, pp. 2656-2660, 2014.
19
K. Nelskylä, A. Yli-Hankala, J. Sjöberg, I. Korhonen and K. Korttila, “Warming of insufflation gas during laparoscopic hysterectomy: effect on body temperature and the autonomic nervous system,” Acta anaesthesiologica Scandinavica, vol. 43, no. 10, pp. 974-978, 1999.
20
R. Savel, S. Balasubramanya, S. Lasheen, T. Gaprindashvili, E. Arabov, R. Fazylov, R. Lazzaro and J. Macura, “Beneficial effects of humidified, warmed carbon dioxide insufflation during laparoscopic bariatric surgery: a randomized clinical trial,” Obesity Surgery, vol. 15, no. 1, pp. 64-69, 2005.
21
N. Nguyen, G. Furdui, N. Fleming, S. Lee, C. Goldman, A. Singh and B. Wolfe, “Effect of heated and humidified carbon dioxide gas on core temperature and postoperative pain: a randomized trial.,” Surgical Endoscopy, vol. 16, no. 7, pp. 1050-1054, 2002.
22
D. Farley, S. Greenlee, D. Larson and J. Harrington, “Double-blind, prospective, randomized study of warmed, humidified carbon dioxide insufflation vs standard carbon dioxide for patients undergoing laparoscopic cholecystectomy,” Archives of surgery, vol. 139, no. 7, pp. 739-743, 2004.
23
T. Sammour, A. Kahokehr, J. Hayes, M. Hulme-Moir and A. Hill, “Warming and humidification of insufflation carbon dioxide in laparoscopic colonic surgery: a double-blinded randomized controlled trial,” Annals of surgery, vol. 251, no. 6, pp. 1024-1033, 2010.
24
M. Hamza, B. Schneider, P. White, A. Recart, L. Villegas, B. Ogunnaike, D. Provost and D. Jones, “Heated and humidified insufflation during laparoscopic gastric bypass surgery: effect on temperature, postoperative pain, and recovery outcomes,” Journal of laparoendoscopic & advanced surgical techniques. Part A. , vol. 15, no. 1, pp. 6-12, 2005.
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T. Beste, J. Daucher and D. Holbert, “Humidified compared with dry, heated carbon dioxide at laparoscopy to reduce pain,” Obstetrics and Gynaecology, vol. 107, no. 2, pp. 263-268, 2006.
26
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27
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41
ORIGINAL_ARTICLE
Severe perineal hidradenitis suppurativa (HS) and anal fistulas. An underrated association?
Abstract Background Due to its multiple forms of debut hidradenitis suppurativa has classically been a diagnostic challenge as well in the differential diagnosis. Prevalence of perianal fistula in patients with hidradenitis suppurativa ranges form 6,6% to 67%. The aim of the study was to assess both conditions. Methods A retrospective chart review from 2000 to 2018 using the ICD-9-CM, coded with 705.83. for patients with hidradenitis suppurativa was conducted. Hurley’s three stage classification was applied. Diagnosis and relevant patient characteristics were assessed and the presence of associated perianal fistula. Endoa-nal ultrasound (EAU) was performed in 61% of the patients with perianal hidradenitis and perianal fistu-la, and magnetic resonance imaging (MRI) in 19%. Results Of 143 cases with hidradenitis, sixty two cases (43,4%) presented perianal (perineal/buttocks) location. Of them 93,5% were men. Twenty-one percent were associated with perianal fistulas being 6 of them complex ones associated with Hurley stage II and III. Treatment for the latter included: loose setons in 4 patients with Crohn’s disease and in 2 non Crohn’s disease with complex fistulas, 4 fistulotomies and 2 fistulectomies in low transphincteric fistulas and 1 with incision and drainage. Conclusion Perianal fistula should be treated according to associated diseases and type of fistula. Association of hidradenitis and perianal fistulas may be higher than expected and the relation of severe hidradenitis with complex perianal fistulas should be studied further. Endoanal ultrasound and MRI may be useful tools to assess HS with complex perianal fistulas, but the iconographic patterns of hidradenitis and Crohn’s disease should be kept in mind as both may be associated.
https://colorectalresearch.sums.ac.ir/article_46748_f06639b2064833ea9dc0cf2ac4bdc7ac.pdf
2020-06-01
88
92
10.30476/acrr.2020.46748
Hidradenitis suppurativa
Anal Fistula
Crohn’s disease
diagnosis of hidradenitis suppurativa
Juan Carlos
Bernal-Sprekelsen
jcbs94@gmail.com
1
Consorcio Hospital General Universitario de Valencia
LEAD_AUTHOR
Laura
Gómez Romero
gomez_laurom@gva.es
2
Hospital Universitario de La Ribera/Alzira
AUTHOR
Jorge
Tárraga Soriano
jotaso27@gmail.com
3
Consorcio Hospital General Universitario de Valencia
AUTHOR
José
Puche Plà
lpuchepla@hotmail.com
4
Consorcio Hospital General Universitario de Valencia
AUTHOR
Guillermo Felipe
Valderas Cortés
valderas_gui@gva.es
5
Consorcio Hospital General Universitario de Valencia
AUTHOR
Antonio
Melero Abellán
antoniomelero86@yahoo.es
6
Consorcio Hospital General Universitario de Valencia
AUTHOR
[1] EMA/CHMP/177541/2015. Committee for Medicinal Products for Human Use. Extension of indication variation assessment report. Invented name: Humeral. Procedure Nº. EMEA/H/C/000481/II/0134 European Medicines Agency. Science Medicines Health. London E14 SEU, United Kingdom.
1
[2] Iniciativa estratégica de salud para la definición del estándar óptimo de cuidados. Para los pacientes con hidradenitis supurativa. Hércules. Iniciativa estratégica en hidradenitis supurativa 2017. Ed: Draft Editores, Madrid. ISBN: 978-84-88014-40-5
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[3] Ardon CB, Molenaar C, Van Straalen KR, Scholtes VC, Prens EP, Van der Zee HH. High prevalence of hidradenitis suppurativa in patients with perianal fistula. Int J ColorectalDis 2019;34:1337–1339. 10.1007/s00384-019-03313-2.
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[5] Thornton JP, Abcarian H. Surgical treatment of perianal and perineal hidradenitis suppurativa. Dis Colon Rectum 1978; 21(8):573–577
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[6] Church JM, Fazio VW, Lavery IC, Oakley JR, Milsom JW. The differential diagnosis and comorbidity of hidradenitis suppurativa and perianal Crohn’s disease. Int J Colorectal Dis 1993;8(3):117–119
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[7] Hurley H. Axillary hyperhidrosis, apocrine bromhidrosis, hidradenitis suppurativa, and familial benign pemphigus: surgical approach. In: Roenigk RK, Roenigk HH (eds) Roenigk and Roenigk’s dermatologic surgery: principles and practice. Marcel Dekker, New York, 1989
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[8] Bernal JC, Tárraga J, Gómez L, Cifre C, Melero A, Ivorra P, Gª-Coret MªJ, Salvador A, Zaragoza C. Is perineal/perianal hidradenitis suppurativa (HS) associated with anal fistula? Colorectal Dis 2019;21(Suppl.3), 33-128
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[9] Martorell A, Segura Palacios JM. Ecografía de la hidradenitis supurativa. Actas Dermosifiliogr (106 Suppl) 1:49–59. Martorell, A., & Segura Palacios, J. M. (2015). Ecografía de la hidradenitis supurativa. Actas Dermo-Sifiliográficas, 2015;106, 49–59. doi:10.1016/s0001-7310(16)30007-2
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[10] Wortsman X (2016) Imaging of Hidradenitis Suppurativa. Dermatol Clin 34: 59–68. doi: 10.1016/j.det.2015.08.003
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[11] Kolodziejczak M, Sudol-Szopinska I, Wilczynska A, Bierca J. Utility of transperineal and anal ultrasonography in the diagnosis of hidradenitis suppurativa and its differentiation from a rectal fistula. Postepy Hig Med Dosw 2012;66:838-42. doi: 10.5604/17322693.1019537.
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[12] Bernal-Sprekelsen JC, López J, Esclápez P, Trullenque R. Fistulectomía tipo Core out modificada. Abordaje personal. Cir Esp 2000; 67:462-465
12
[13] Monnier L, Dohan A, Amara N, Zagdanski AM, Drame M, Soyer P, Hoeffel C. Anoperineal disease in Hidradenitis Suppurativa : MR imaging distinction from perianal Crohn’s disease. European Radiology 2017;27(10): 4100–4109. doi: 10.1007/s00330-017-4776-1.
13
[14] Griffin N, Williams AB, Anderson S, Irving PM, Sanderson J, Desai N, Goh V. Hidradenitis Suppurativa. MRI Features in Anogenital Disease. Diseases of the Colon & Rectum 2014;57(6): 762–771. doi: 10.1097/DCR.0000000000000131.
14
[15] Derruau S, Renard Y, Pron H, Taiar R, Abdi E, Polidori G, Lorimier S. Combining Magnetic Resonance Imaging (MRI) and Medical Infrared Thermography (MIT) in the pre- and per-operating management of severe Hidradenitis Suppurativa (HS) Photodiagnosis and Photodynamic Therapy 2018;23: 9-11. doi: 10.1016/j.pdpdt.2018.05.007.
15
[16] Scholl L, Hessam S, Bergmann U. Surgical Treatment of Sinus Tracts and Fistulas in Perianal Hidradenitis Suppurativa. Journal of Cutaneous Medicine and Surgery 2018;22(2): 239–241. doi: 10.1177/1203475417746122
16
[17] Lamb AA, Kennedy NA, Raine T, Hendy PA, Smith PJ, Limdi JK, et al. British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults. Gut 2019;0:1-106. doi: 10.1136/gutjnl-2019-318484
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[18] Williams G, Williams A, Tozer P, Phillips r, Ahmead A, Jayne D, Mawell-Armstrong C. The
18
treatment of anal fistula: second ACPGBI Position Statement-2018. Colorectal Dis 2018;20 (Suppl. 3):5-3. doi:10.1111/codi.14054
19
[19] Herreros MD, García-Olmo D, Guadalajara H, Georgiev-Hristov T, Brandariz L, García-Arranz M. Stem cell therapy: a compassionate use program in perianal fistula. Hindawi Stem Cells International 2019;1-6; doi.org/10.1155/2019/6132340
20
ORIGINAL_ARTICLE
Short term outcomes of Endoscopic Pilonidal Sinus Laser Treatment: a Single Centre experience.
Short term outcomes of Endoscopic Pilonidal Sinus Laser Treatment: a Single Centre experience. Pilonidal sinus (PS) is a widespread pathologic condition. The etiology of Pilonidal Disease (PD) is in favor of an acquired cause. Multiple surgical options have been advocated. In the last few years a minimally invasive approach to PD has been proposed. We performed a retrospective analysis of short-term surgical outcomes of combining EpSiT approach with the use of a radial laser fiber in the treatment of PD in a Single Centre. At our Proctology Centre, we performed 10 consecutive Endoscopic Pilonidal Sinus Laser Treatment procedures in the period from march 2019 to september 2019. The review of our initial experience suggests that the combination of fistuloscopy and laser ablation in treating fistulizing PD is feasible, safe and reproducible. Pilonidal sinus (PS) is a widespread pathologic condition. The etiology of Pilonidal Disease (PD) is in favor of an acquired cause. Multiple surgical options have been advocated. In the last few years a minimally invasive approach to PD has been proposed. We performed a retrospective analysis of short-term surgical outcomes of combining EpSiT approach with the use of a radial laser fiber in the treatment of PD in a Single Centre. At our Proctology Centre, we performed 10 consecutive Endoscopic Pilonidal Sinus Laser Treatment procedures in the period from march 2019 to september 2019. The review of our initial experience suggests that the combination of fistuloscopy and laser ablation in treating fistulizing PD is feasible, safe and reproducible
https://colorectalresearch.sums.ac.ir/article_46700_0bf97a481951cd861d9c234bc2e49b30.pdf
2020-06-01
93
96
10.30476/acrr.2020.46700
Pilonidal Disease
Laser ablation
Fistuloscopy
Minimally Invasive Surgery
Francesco
Cantarella
fcanta81@gmail.com
1
Unit of Proctology, Ospedali Privati Forlì, 47121, Forlì, Italy
LEAD_AUTHOR
Enrico
Magni
enrico@gmail.com
2
Unit of Proctology, Ospedali Privati Forlì, 47121, Forlì, Italy
AUTHOR
Søndenaa K, Andersen E, Nesvik I, Søreide JA (1995) Patient characteristics and symptoms in chronic pilonidal sinus disease. Int J Colorectal Dis 10(1):39–42.
1
Thompson MR, Senapati A, Kitchen P (2011) Simple day-case surgery for pilonidal sinus disease. Br J Surg 98:198–209 6.
2
Al-Khayat H, Al-Khayat H, Sadeq A et al (2007) Risk factors for wound complications in pilonidal sinus procedures. J Am Coll Surg 205:439–444 7.
3
Harlak A, Mentes O, Kilic S, Coskun K, Duman K, Yilmaz F (2010) Sacrococcygeal pilonidal disease: analysis of previously proposed risk factors. Clinics 65:125–131.
4
Chintapatla S, Safarani N, Kumar S, Haboubi N (2003) Sacrococcygeal pilonidal sinus: historical review, pathological insight and surgical options. Tech Coloproctol 7:3–8.
5
Segre D, Pozzo M, Perinotti R, Roche B (2015) The treatment of pilonidal disease: guidelines of the Italian Society of Colorectal Surgery (SICCR). Tech Coloproctol 19:607–613.
6
Shabbir J, Chaudhary BN, Britton DC (2011) Management of sacrococcygeal pilonidal sinus disease: a snapshot of current practice. Int J Colorectal Dis 26(12):1619–1620 7.
7
McCallum IJ, King PM, Bruce J (2008) Healing by primary closure versus open healing after surgery for pilonidal sinus: systematic review and meta-analysis. BMJ 336(7649):868–871.
8
Meinero P, Mori L, Gasloli G (2014) Endoscopic pilonidal sinus treatment (E.P.Si.T.). Tech Coloproctol 18(4):389–392
9
Georgiou GK (2018) Outpatient laser treatment of primary pilonidal disease: the PiLaT technique. Tech Coloproctol 22:773–778.
10
Giarratano G et al (2017) Endoscopic pilonidal sinus treatment: long-term results of a prospective series. JSLS 21(3):e2017.
11
Emile SH et al (2018) Endoscopic pilonidal sinus treatment: a systematic review and meta-analysis. Surg Endosc 32(9):3754–3762.
12
Meinero P, Stazi A, Carbone A, Fasolini F, Regusci L, La Torre M. Endoscopic pilonidal sinus treatment: a prospective multicentre trial. Colorectal Dis. 2016;18:O164–O170.
13
Wilhelm A, Fiebig A, Krawczak M. Five years of experience with the FiLaC™ laser for fistula-in-ano management: long-term follow-up from a single institution.Tech Coloproctol. 2017 Apr;21(4):269-276.
14
ORIGINAL_ARTICLE
The Fundamental Role of Postoperative Critical Care in Gynecologic Oncology Surgery: A Brief Report
The value of postoperative critical care in gynecologic oncology surgery is crucial for the patient’s further postoperative course. For that reason different levels of postoperative care should exist, in order to identify in an early stage the possible complications and handle them properly . Strict indications of who should be admitted or not, should be defined and surgeons as well anesthesiologists should be aware of them. On the other hand, longer stay in hospital increases the likelihood of complications such as nosocomial infections and late ambulation, increasing morbidity and mortality. Therefore, longer stay in critical care units should be avoided, by predicting if patients are able to move to the general ward and later exit from the hospital. The next step is to set strict protocols for the indications of admission and decreased hospitalization by an accepted scientific team. These protocols should be applied universally in order to achieve the best possible outcomes in patients’ postoperative course.
https://colorectalresearch.sums.ac.ir/article_46701_caa34233d868b3f3f76040edd8d5ce51.pdf
2020-06-01
97
100
10.30476/acrr.2020.46701
Critical care
Gyn/oncology
postoperative care
Konstantinos
Koukoubanis
ntinoskoukoubanis@hotmail.com
1
1st Department of obstetrics / gynecology
National and Kapodistrian University of Athens
Aleksadra Hospital, Athens, Greece
LEAD_AUTHOR
Vasiliki
Bibasi
vassiampi@gmail.com
2
Departement of Pediatrics Asklepieion Hospital Athens,Greece
AUTHOR
Nikolaos
Thomakos
thomakir@hotmail.com
3
Devision of GYN/Oncology 1st Departement of Obstetrics/Gynecology , Ntional and Kapoditrian University of Athens, Aleskandra Hospital, Athens, Greece
AUTHOR
1. Amir, M., Shabot, M. M., & Karlan, B. Y. (1997). Surgical intensive care unit care after ovarian cancer surgery: An analysis of indications. American Journal of Obstetrics and Gynecology. https://doi.org/10.1016/S0002-9378(97)70366-1
1
2. Davidovic-Grigoraki, M., Thomakos, N., Haidopoulos, D., Vlahos, G., & Rodolakis, A. (2017). Do critical care units play a role in the management of gynaecological oncology patients? The contribution of gynaecologic oncologist in running critical care units. In European Journal of Cancer Care. https://doi.org/10.1111/ecc.12438.
2
3. Eisenkop, S. M., Spirtos, N. M., & Lin, W. C. M. (2006). “Optimal” cytoreduction for advanced epithelial ovarian cancer: A commentary. In Gynecologic Oncology. https://doi.org/10.1016/j.ygyno.2006.07.004
3
4. Heinonen, S., Tyrváinen, E., Penttinen, J., Saarikoski, S., & Ruokonen, E. (2002). Need for critical care in gynaecology: A population-based analysis. Critical Care. https://doi.org/10.1186/cc1525
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5. Leath, C. A., Kendrick IV, J. E., Numnum, T. M., Straughn, J. M., Rocconi, R. P., Sfakianos, G. P., & Lang, J. D. (2006). Outcomes of gynecologic oncology patients admitted to the intensive care unit following surgery: A university teaching hospital experience. International Journal of Gynecological Cancer. https://doi.org/10.1111/j.1525-1438.2006.00702.x
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6. Montz, F. J., Holschneider, C. H., Solh, S., Schuricht, L. C., & Monk, B. J. (1994). Small bowel obstruction following radical hysterectomy: Risk factors, incidence, and operative findings. Gynecologic Oncology. https://doi.org/10.1006/gyno.1994.1097
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7. Sobol, J. B., & Wunsch, H. (2011). Triage of high-risk surgical patients for intensive care. In Critical Care. https://doi.org/10.1186/cc9999
7
8. Thomakos, N., Zacharakis, D., Rodolakis, A., Zagouri, F., Papadimitriou, C. A., Bamias, A., Dimopoulos, M. A., Haidopoulos, D., Vlahos, G., & Antsaklis, A. (2014). Gynecologic oncology patients in the surgical high dependency unit: An analysis of indications. Archives of Gynecology and Obstetrics. https://doi.org/10.1007/s00404-014-3180-1
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ORIGINAL_ARTICLE
Acute Aortic Thrombosis Following Anterior Resection - A Rare Complication
INTRODUCTION : Anterior resection is a commonly performed surgery for rectal cancer worldwide. It is associated with a wide spectrum of complications which include haemorrhage, pelvic sepsis, wound infection, anastomotic breakdown, deep vein thrombosis, peripheral nerves injury, impotence and urological dysfunction. However acute aortic thrombosis post anterior resection is a very rare complication. CASE PRESENTATION : We report a rare case of aortic thrombosis in a 67 year old gentleman following anterior resection for rectal cancer. DISCUSSION : We also discuss its possible causes as there are many postulations to the cause of this devastating complication. Prolonged surgery, abnormal blood coagulation in cancer patient, lithotomy position and the presence of peripheral vascular disease are predisposing factors contributing to this rare acute aortic thrombosis in our patient. A standard routine neurovascular examination of the extremities should be done in the postoperative period to help detect early any neurovascular complication. The use of prophylactic anticoagulant such as fondaparinux, low molecular weight heparin or low dose unfractionated heparin are strongly recommended in high risk surgery patients undergoing a major surgery which helps prevent thromboembolic episode following surgery.
https://colorectalresearch.sums.ac.ir/article_46754_1682a29feecb39765ebb9f315f3b248d.pdf
2020-06-01
101
103
10.30476/acrr.2020.46754
Anterior resection
aortic thrombosis
Rectal Cancer
surgical management
Muhamad Izwan
Ismail
izwanismail99@gmail.com
1
Department of Surgery, Hospital Sultanah Bahiyah, Alor Setar, Malaysia
LEAD_AUTHOR
Hoong Yin
Chong
hychong@hotmail.com
2
Department of Surgery, Hospital Sultanah Bahiyah, Alor Setar, Malaysia.
AUTHOR
Wan Khamizar
Wan Khazim
khamizar@gmail.com
3
Department of Surgery, Hospital Sultanah Bahiyah, Alor Setar, Malaysia
AUTHOR
Casillas S, Nicholson JD. Aortic thrombosis after low anterior resection for rectal cancer: report of a case. Dis Colon Rectum. 2002;45(6):829-832.
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