ORIGINAL_ARTICLE
Molecular Biomarkers of Colorectal Cancer: A Review of Published Articles From Iran
Context Colorectal cancer is one of the most common cancers worldwide (the third most common cancer in the world) and is especially more common in Western countries; however, its incidence has been increased significantly during the last few years in Eastern countries such as Iran and considered as one of the five common cancers in this country. According to molecular pathways, numerous biomarkers have been identified for colorectal cancers which help patients’ management. Evidence aquisition In this study, we tried to review published articles about the molecular biomarkers of colorectal cancer from Iran. We searched medical databases such as google scholar, Scopus, PubMed, Magiran, SID and Iran Medex for keywords of “colon cancer, KRAS, BRAF, mismatch repair gene, Microsatellite instability, molecular genetics, molecular pathogenesis, biomarker and Iran” to find studies published about colorectal cancers from Iran regarding molecular biomarkers. Conclusion This study showed that molecular biomarkers in colorectal cancer of Iranian patients are not so different from Western population.
https://colorectalresearch.sums.ac.ir/article_45493_0164fa998e4cce2578943d713289c81d.pdf
2015-09-01
0
0
10.17795/acr-30100
Biological Markers
Colorectal cancer
cancer
Bita
Geramizadeh
1
Department of Pathology, Transplant Research Center, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, IR Iran
LEAD_AUTHOR
ORIGINAL_ARTICLE
Comparison of Infection Incidence Between Appendectomy Skin Incisions Sutured by Nylon and Polyglactin (Vicryl)
Background Suturing quality and reducing its complications and resulting infection have always been a major concern of surgeons. Many of them have prohibited applying polyfilament and absorbable suturing materials. Objectives In this study, we compared skin wound infection rate and other complications in two groups of post appendectomy patients whom were treated with two types of suturing materials - conventionally used Nylon and absorbable braided polyglactin (Vicryl) - and wound healing, existence of complication and recovery course of treated patients were surveyed. Patients and Methods A total of 130 patients who underwent appendectomy were divided into two groups of 645 members, each. Patients in group A had their incisions closed by separate sutures (mattress method) by vicryl, while patients in group B had their surgical incisions were closed in the same method, by nylon sutures. Any signs and symptoms of surgical site wound infection like inappropriate pain, redness, discharge, bulging, and unhealing wound were checked during hospital stay and on the 7th - 9th day postoperatively. Results The postsurgical complication and infections rates were similar between the two groups. Conclusions Vicryl sutures can safely be used for skin and subcutaneous wound suturing even when our surgery site is not ideally clean.
https://colorectalresearch.sums.ac.ir/article_45494_7bc78397f80d05ef1120f03527461a32.pdf
2015-09-01
0
0
10.17795/acr-30179
Polyglactin 910
Wound Infection
Sutures
Alireza
Golchini
1
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz , IR Iran
AUTHOR
Habib Alah
Nikzad Jamnani
2
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz , IR Iran
AUTHOR
Sajjad
Ahmadi
3
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz , IR Iran
AUTHOR
Elham
Karimi
4
Department of Surgery, Nursing Faculty, Shiraz University of Medical Sciences, Shiraz, IR Iran
AUTHOR
Saeedeh
Pourahmad
5
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz , IR Iran
AUTHOR
Alireza
Safarpour
6
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz , IR Iran
AUTHOR
Zahra
Zabangirfard
7
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz , IR Iran
AUTHOR
Leila
Ghahramani
8
LEAD_AUTHOR
ORIGINAL_ARTICLE
Cryptosporidiosis and Colorectal Cancer
Background Suturing quality and reducing its complications and resulting infection have always been a major concern of surgeons. Many of them have prohibited applying polyfilament and absorbable suturing materials. Objectives In this study, we compared skin wound infection rate and other complications in two groups of post appendectomy patients whom were treated with two types of suturing materials - conventionally used Nylon and absorbable braided polyglactin (Vicryl) - and wound healing, existence of complication and recovery course of treated patients were surveyed. Patients and Methods A total of 130 patients who underwent appendectomy were divided into two groups of 645 members, each. Patients in group A had their incisions closed by separate sutures (mattress method) by vicryl, while patients in group B had their surgical incisions were closed in the same method, by nylon sutures. Any signs and symptoms of surgical site wound infection like inappropriate pain, redness, discharge, bulging, and unhealing wound were checked during hospital stay and on the 7th - 9th day postoperatively. Results The postsurgical complication and infections rates were similar between the two groups. Conclusions Vicryl sutures can safely be used for skin and subcutaneous wound suturing even when our surgery site is not ideally clean.
https://colorectalresearch.sums.ac.ir/article_45495_0cdeab58aae9d391ce30d37132913a38.pdf
2015-09-01
0
0
10.17795/acr-31871
Cryptosporidiosis
cancer
Colon
Rectum
Sim Sai
Tin
simsaitin@gmail.com
1
LEAD_AUTHOR
Viroj
Wiwanitkit
2
Tropical Medicine Department, Hainan Medical University, Haikou, China
AUTHOR
ORIGINAL_ARTICLE
Conservative Management of Anterior Abdominal Stab Wounds
Background Suturing quality and reducing its complications and resulting infection have always been a major concern of surgeons. Many of them have prohibited applying polyfilament and absorbable suturing materials. Objectives In this study, we compared skin wound infection rate and other complications in two groups of post appendectomy patients whom were treated with two types of suturing materials - conventionally used Nylon and absorbable braided polyglactin (Vicryl) - and wound healing, existence of complication and recovery course of treated patients were surveyed. Patients and Methods A total of 130 patients who underwent appendectomy were divided into two groups of 645 members, each. Patients in group A had their incisions closed by separate sutures (mattress method) by vicryl, while patients in group B had their surgical incisions were closed in the same method, by nylon sutures. Any signs and symptoms of surgical site wound infection like inappropriate pain, redness, discharge, bulging, and unhealing wound were checked during hospital stay and on the 7th - 9th day postoperatively. Results The postsurgical complication and infections rates were similar between the two groups. Conclusions Vicryl sutures can safely be used for skin and subcutaneous wound suturing even when our surgery site is not ideally clean.
https://colorectalresearch.sums.ac.ir/article_45496_856824598d5513dd2f8e6815fcc3d9b7.pdf
2015-09-01
0
0
10.17795/acr-32059
Abdominal
Management
Wounds
Stab
Seyed Vahid
Hosseini
1
Department of Surgery, Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
AUTHOR
Seyed Hesamaddin
Banihashemi
colorectal@sums.ac.ir
2
Department of Surgery, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, IR Iran
LEAD_AUTHOR
Shahla
Fereidooni
3
Department of Surgery, Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
AUTHOR
ORIGINAL_ARTICLE
Melilotus officinalis L. Protects Ulcerative Colitis in Rats
Background Suturing quality and reducing its complications and resulting infection have always been a major concern of surgeons. Many of them have prohibited applying polyfilament and absorbable suturing materials. Objectives In this study, we compared skin wound infection rate and other complications in two groups of post appendectomy patients whom were treated with two types of suturing materials - conventionally used Nylon and absorbable braided polyglactin (Vicryl) - and wound healing, existence of complication and recovery course of treated patients were surveyed. Patients and Methods A total of 130 patients who underwent appendectomy were divided into two groups of 645 members, each. Patients in group A had their incisions closed by separate sutures (mattress method) by vicryl, while patients in group B had their surgical incisions were closed in the same method, by nylon sutures. Any signs and symptoms of surgical site wound infection like inappropriate pain, redness, discharge, bulging, and unhealing wound were checked during hospital stay and on the 7th - 9th day postoperatively. Results The postsurgical complication and infections rates were similar between the two groups. Conclusions Vicryl sutures can safely be used for skin and subcutaneous wound suturing even when our surgery site is not ideally clean.
https://colorectalresearch.sums.ac.ir/article_45497_1219f14dab88fef236d067e1af1423af.pdf
2015-09-01
0
0
10.17795/acr-32500
Ulcerative colitis
Antioxidant
Hajar
Khazraei
1
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
AUTHOR
Seyed Vahid
Hosseini
colorectal@sums.ac.ir
2
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
LEAD_AUTHOR
Fahimeh
Hajhosseini
3
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
AUTHOR
ORIGINAL_ARTICLE
Perianal Paget’s Disease in a Forty-Five-Year-Old Man and Review of the Literature
Introduction Extramammary Paget’s disease is a rare neoplasm of the skin that might develop in perianal region. Although different management options are available, wide local excision is still the method of choice. Case Presentation A 45-year-old man presented with perianal itchy lesions for one year with no response to local treatments. Perianal Paget’s disease was diagnosed by performing a surgical biopsy. Wide excision and flap reconstruction was done, while loop sigmoid colostomy was performed for fecal diversion. Re-excision of the involved margins was performed during the second operation. Conclusions A good outcome and no recurrence or complications was noticed in a follow-up period of 24 months. It is important to consider this uncommon disease as a probable diagnosis when evaluating a perianal lesion.
https://colorectalresearch.sums.ac.ir/article_45498_f91421da8a4ba79cc7eef48e3b982e87.pdf
2015-09-01
0
0
10.17795/acr-29093
Paget Disease Extramammary
Perianal Glands
Local Excision
Yavar
Shams Hojjati
1
Department of Surgery, Mashhad University of Medical Sciences, Mashhad, IR Iran
AUTHOR
Abbas
Abdollahi
abdollahia@mums.ac.ir
2
LEAD_AUTHOR
Ghodratollah
Maddah
3
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
AUTHOR
Asieh Sadat
Fattahi
4
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
AUTHOR