Shiraz University of Medical Sciences
Iranian Journal of Colorectal Research
2783-2430
3
2
2015
06
01
Combined Technique in the Management of Complex Pilonidal Disease
0
0
EN
Seyed Vahid
Hosseini
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Alimohamamad
Bananzadeh
0000-0003-1116-2294
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
bananzadeh@gmail.com
10.17795/acr-21447
Context Colorectal cancer (CRC) is the third most prevalent cancer worldwide which is less common in the Middle East. It is also the second leading cause of cancer-related mortality and represents a major public health problem in developed countries. Objectives The present review aimed to explore the differences among the reports on number and age standardized incidences of CRC in both sexes in different areas of Iran to find the incidence trend of this cancer. Data Sources All the published reports citing the incidence of CRC in Iran were collected by conducting a literature search in international databases. Study Selection English articles were included where there was a clear definition of the population of patients under study and where the criteria for diagnosing CRC were well described. Data Extraction One author read each paper and extracted several studies and then the studies suitable for inclusion were reported in three categories. Results We identified 181 independent studies dating back to 2003; 168 full text articles were assessed for eligibility. However, 136 full text articles were excluded due to different reasons. Finally, 26 studies were suitable for inclusion in the analysis. The highest and lowest (age standardized rates) ASRs were respectively 3.4 and 2.6 in males and 11.42 and 10.56 in females. Time showed a slightly increasing trend in recent years. Conclusions Although Iran was expected to have a low incidence rate of CRC, recent studies revealed a slightly increasing trend for the incidence rate of CRC. This finding shows the necessity to consider CRC screening as an important issue in health policy priorities.
Pilonidal Disease,Fistula,Abscess,Surgical flaps
https://colorectalresearch.sums.ac.ir/article_45486.html
https://colorectalresearch.sums.ac.ir/article_45486_3fd8ea2be0fe953060dc004926f61f8b.pdf
Shiraz University of Medical Sciences
Iranian Journal of Colorectal Research
2783-2430
3
2
2015
06
01
Frequency of Different Psychiatric Disorders in Patients With Functional Bowel Disorders: A Short Report
0
0
EN
Bahareh
Fakhraei
Non-Communicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, IR Iran
Ali
Firouzabadi
Department of Psychiatry, Research Center for Psychiatry and Behavioral Sciences, Hafez Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran
Mojtaba
Farjam
Department of Medical Pharmacology, School of Medicine, Fasa University of Medical Sciences, Fasa, IR Iran
Mohammad Reza
Fattahi
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Mohamad Hasan
Kazemi
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Mahvash
Alizade Naini
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Maryam
Moini
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
dornam@hotmail.com
10.17795/acr-27621
Background Functional gastrointestinal (GI) disorders are very common and many patients with such disorders are not satisfied with treatment outcomes. Psychological aspects of functional disorders need special attention that may play an important role in patient management. Objectives In this study, psychology evaluation was performed for a population of patients with functional bowel disorders. Patients and Methods One hundred patients with functional bowel disorders including 50 patients with irritable bowel syndrome (IBS) referred to GI clinics were candidates for psychiatry evaluation; of those 60 patients completed the study. Psychiatric disorders were diagnosed using a structured clinical interview based on diagnostic and statistical manual of mental disorders IV (DSM IV). Results Of 60 patients with functional bowel disorders (including 39 IBS), 51 (85%) were diagnosed with at least one psychiatry disorder. The most common disorders were dysthymia (25%) and obsessive-compulsive disorder (20%). There was no significant difference between IBS patients and other functional bowel disorders regarding the prevalence of psychiatric disorders. Conclusions Psychiatric disorders are very prevalent among patients with functional bowel disorders. Prompt diagnosis and appropriate management of associated psychiatric disorders along with GI targeted treatments may lead to a better outcome in these patients.
Functional Gastrointestinal Disorders,Mental disorders,Irritable bowel syndrome
https://colorectalresearch.sums.ac.ir/article_45487.html
https://colorectalresearch.sums.ac.ir/article_45487_9b30dcec5bc9e726137acf937cbed894.pdf
Shiraz University of Medical Sciences
Iranian Journal of Colorectal Research
2783-2430
3
2
2015
06
01
Is Clinical Evaluation Sufficient for Decision Making in Patients With Penetrating Abdominal Trauma?
0
0
EN
Ahmad
Izadpanah
0000-0003-2029-0829
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
drahmadizadpanah@gmail.com
10.17795/acr-28187
Background Functional gastrointestinal (GI) disorders are very common and many patients with such disorders are not satisfied with treatment outcomes. Psychological aspects of functional disorders need special attention that may play an important role in patient management. Objectives In this study, psychology evaluation was performed for a population of patients with functional bowel disorders. Patients and Methods One hundred patients with functional bowel disorders including 50 patients with irritable bowel syndrome (IBS) referred to GI clinics were candidates for psychiatry evaluation; of those 60 patients completed the study. Psychiatric disorders were diagnosed using a structured clinical interview based on diagnostic and statistical manual of mental disorders IV (DSM IV). Results Of 60 patients with functional bowel disorders (including 39 IBS), 51 (85%) were diagnosed with at least one psychiatry disorder. The most common disorders were dysthymia (25%) and obsessive-compulsive disorder (20%). There was no significant difference between IBS patients and other functional bowel disorders regarding the prevalence of psychiatric disorders. Conclusions Psychiatric disorders are very prevalent among patients with functional bowel disorders. Prompt diagnosis and appropriate management of associated psychiatric disorders along with GI targeted treatments may lead to a better outcome in these patients.
Wounds,Penetrating,Trauma,Peritonitis,Laparotomy,Peritoneal lavage
https://colorectalresearch.sums.ac.ir/article_45488.html
https://colorectalresearch.sums.ac.ir/article_45488_02c3c3c1288e07faf87b322de611e614.pdf
Shiraz University of Medical Sciences
Iranian Journal of Colorectal Research
2783-2430
3
2
2015
06
01
Comparison of Oncologic Short Term Results of Laparoscopic Versus Open Surgery of Rectal Cancer
0
0
EN
Ehsan
Solati
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
Ghodratollah
Maddah
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
Abbas
Abdollahi
abdollahia@mums.ac.ir
Alireza
Tavassoli
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
Masoumeh
Safaei
Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Mehdi
Jabbari Nooghabi
10.17795/acr-28794
Background Today, with improvements in laparoscopy technique, surgery of rectal cancer is performed by laparoscopy. Objectives This study was performed to evaluate oncologic results of open versus laparoscopic surgery of rectal cancer in terms of resection margins, removal of lymph nodes and recurrence rate. Patients and Methods This descriptive-analytic study was performed on 88 patients with middle and lower rectal cancer in the two equivalent groups of laparoscopic and open surgery in Mashhad Ghaem and Omid hospitals during 2011 - 2013. Information including age, sex, number of removed and involved lymph nodes, proximal, distal, and radial margins, tumor stage and location, recurrence and disease-free survival collected in the questionnaire and analyzed using descriptive statistics and frequency distribution tables and t-test. Results Both groups of open and laparoscopic surgery had similar characteristics of age, sex, recurrence and disease-free survival, tumor margins and one-year mortality. The number of removed and involved lymph nodes was higher in the laparoscopic group (5.16 vs. 3.55, respectively, with P < 0.050, and 1.74 vs. 0.59 with P = 0.023), but the ratio of involved lymph nodes to the total number of removed lymph nodes was not different between the two groups (LNR) (P = 0.071). Tumor stage was higher in the laparoscopic group and most were in stages II and III (P < 0.001). Conclusions Laparoscopic surgery is an effective technique for safe margin and removing lymph nodes in rectal cancer.
Rectal Neoplasms,Open Surgery,Laparoscopy
https://colorectalresearch.sums.ac.ir/article_45489.html
https://colorectalresearch.sums.ac.ir/article_45489_0793fad1719991b7eeacc0c507cf8153.pdf
Shiraz University of Medical Sciences
Iranian Journal of Colorectal Research
2783-2430
3
2
2015
06
01
Laparoscopy and Intra-Abdominal Sepsis
0
0
EN
Peter Edward
Coyne
Colorectal Unit, Department of Surgery, Northumbria Healthcare NHS Trust, Northumberland, UK
petercoyne@doctors.org.uk
Reza
Kalbassi
Colorectal Unit, Department of Surgery, Northumbria Healthcare NHS Trust, Northumberland, UK
10.17795/acr-28983
Context Intra-abdominal sepsis has significant morbidity and mortality. In the developed world, there are many common causes originating from the lower gastrointestinal tract including diverticular disease, appendicitis, perforated cancers, and inflammatory bowel disease. It has a high cost and is associated with high levels of significant morbidity and mortality. Management options include radiologic drainage and surgical options include resection for more widespread sepsis. Laparoscopic surgery has increased and has been useful in elective setting. Its use in the emergency setting is less evaluated. Evidence Acquisition Evidence was acquired by searching online medical databases including Pubmed, Medline and Embase. Results Laparoscopic surgery has been shown to have a role in the acute setting. Studies show it has become the gold standard in the appendicitis. High quality Randomized controlled trials are in short supply but observational and cohort studies have shown equivalence and with increasing experience complication rates are reduced. Evidence is also increasing in the management of diverticular disease, crohn’s and ulcerative colitis as well as post-operative complication management and acute presentations of colorectal cancer. Conclusions Laparoscopic surgery is feasible in the management of intra-abdominal sepsis. It has become the new accepted standard in the management of appendicitis, and is safe, feasible and increasing in the management of complex diverticular disease, acute IBD and colorectal cancer in the emergency and post-operative setting.
Diverticulitis,Appendicitis,Laparoscopy,Crohn’s disease,Colorectal cancer,Ulcerative colitis
https://colorectalresearch.sums.ac.ir/article_45490.html
https://colorectalresearch.sums.ac.ir/article_45490_06f5c9d7e66dcdc6f48d93d6692a0a29.pdf
Shiraz University of Medical Sciences
Iranian Journal of Colorectal Research
2783-2430
3
2
2015
06
01
Extramedullary Hematopoiesis in a Man With β-Thalassemia: An Uncommon Cause of an Adrenal Mass
0
0
EN
Shahryar
Zeighami
Department of Urology, Shiraz University of Medical Sciences, Shiraz, IR Iran
Seyed Ali
Eslahi
alieslahi@yahoo.com
Mohammad Mehdi
Hosseini
Department of Urology, Shiraz University of Medical Sciences, Shiraz, IR Iran
Ali
Ariafar
Department of Urology, Shiraz University of Medical Sciences, Shiraz, IR Iran
Sara
Pakbaz
Pathology Department, Shiraz University of Medical Sciences, Shiraz, IR Iran
Mohsen
Rastegari
Department of Urology, Shiraz University of Medical Sciences, Shiraz, IR Iran
Hajar
Khazraei
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
10.17795/acr-29003
Introduction Extramedullary hematopoiesis (EMH) commonly occurs in the spleen, liver and lymph nodes. Rare cases of EMH in the adrenal gland have been reported. Case Presentation We report the case of a 33-year-old man from the South of Iran suffering from major β-thalassemia, who underwent open left adrenalectomy and the histopathology revealed EMH. Conclusions In patients in which a history of hematologic disorders exists, careful imaging and hormonal assay should be done to certify a diagnosis of EMH. However, the surgical management becomes inevitable in certain cases.
Extramedullary hematopoiesis,Thalassemia,Adrenal
https://colorectalresearch.sums.ac.ir/article_45491.html
https://colorectalresearch.sums.ac.ir/article_45491_c651d18784ba0a7fd4222ae36e699763.pdf
Shiraz University of Medical Sciences
Iranian Journal of Colorectal Research
2783-2430
3
2
2015
06
01
Antioxidant and Anti-Inflammatory Effects of Gel and Aqueous Extract of Melilotus officinalis L. in Induced Ulcerative Colitis: A Rattus norvegicus Model
0
0
EN
Ali Reza
Safarpour
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Fatemeh
Kaviyani
Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Masood
Sepehrimanesh
sepehrimaneshmasood@gmail.com
Nasrollah
Ahmadi
Department of Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, IR Iran
Omid
Koohi Hosseinabadi
Laboratory Animals Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Nader
Tanideh
Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Najmeh
Showraki
Department of Oral Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, IR Iran
10.17795/acr-29511
Background Ulcerative colitis (UC) is a chronic condition of intestine illness accompanied by some unknown etiology with different immune, genetic and environmental factors. Objectives The current study aimed to evaluate the antioxidant and anti-inflammatory effects of the Melilotus officinalis L. in the acetic acid induced UC in rats. Materials and Methods The plant aqueous extraction and high performance liquid chromatography and Ferric Reducing Antioxidant Power (FRAP) assay were performed on aqueous extract to identify its compounds and antioxidant activities. Also, 70 adult male rats were and UC was induced using 3% acetic acid solution. They received different daily doses of M. officinalis L. in two forms (orally, 500 and 1000 mg/kg) and gel extract (10% and 20%). On the 7th day, the colon tissues were examined regarding the macroscopic and histopathology lesions plus oxidative stress and compared to the positive and negative control groups. Results HPLC analysis revealed that five grams of the flower powder contained 9.7 mg gallic acid, 99 mg catechin, 21.9 mg caffeic acid, 0.86 mg chlorogenic acid, 1.13 mg quercetin, 548.9 mg cinnamic acid, 289 mg coumarin and 126 mg p-coumaric acid. The FRAP value of the extract was 2.91 ± 0.14 μM/g. There were significant differences between the group of rats which received the gel or aqueous extract of the flower compared to the negative control group using normal saline and the base gel and they had no significant differences with the positive control group using the Asacol, regarding the pathologic, malondialdehyde, and weight improvements. Conclusions It can be concluded that the M. officinalis L. extract can be used as an effective medicine to treat UC in animal model and also in human subjects.
Colitis,Ulcerative,Inflammation,Extract,Ulcerative colitis,Asacol
https://colorectalresearch.sums.ac.ir/article_45492.html
https://colorectalresearch.sums.ac.ir/article_45492_687c7c06a5ed7d8ef36988fd401ccd90.pdf